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Tumor Suppressive Functions of p53

The majority of human cancers acquire mutations that abrogate the p53 tumor suppressor network and, as a consequence, p53 is one of the most extensively studied proteins in cancer research. Because of its potent tumor suppressive activity, it is widely assumed that a molecular understanding of p53 a...

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Detalhes bibliográficos
Main Authors: Zilfou, Jack T., Lowe, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773645/
https://ncbi.nlm.nih.gov/pubmed/20066118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001883
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