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Non-cell-autonomous tumor suppression by p53
The p53 tumor suppressor can restrict malignant transformation by triggering cell-autonomous programs of cell cycle arrest or apoptosis. p53 also promotes cellular senescence, a tumor suppressive program that involves stable cell cycle arrest and secretion of factors that modify the tissue microenvi...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702034/ https://ncbi.nlm.nih.gov/pubmed/23562644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.03.020 |
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