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Coordinated Tumor Suppression by Chromosome 8p

In this issue of Cancer Cell, Cai et al. use genome editing to study 8p deletions in a mammary epithelial cell model and show that 8p loss of heterozygosity (LOH) attenuates the action of several genes that collectively promote cell invasion and enhance cellular sensitivity to autophagy inhibitors.

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Bibliografische gegevens
Gepubliceerd in:Cancer Cell
Hoofdauteurs: Tschaharganeh, Darjus F., Bosbach, Benedikt, Lowe, Scott W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120649/
https://ncbi.nlm.nih.gov/pubmed/27165739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.04.011
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