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Slugging It out: Fine Tuning the p53-PUMA Death Connection

In response to DNA damage, the tumor suppressor p53 elicits a complex cellular response. In this issue of Cell, Wu et al. (2005) show that the transcription factor SLUG is induced by p53 and protects hematopoietic progenitor cells from apoptosis triggered by DNA damage. SLUG exerts this protective r...

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Publicat a:Cell
Autors principals: Zilfou, Jack T., Spector, Mona S., Lowe, Scott W.
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578637/
https://ncbi.nlm.nih.gov/pubmed/16286002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2005.11.003
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