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MPP(+)-induces PUMA- and p53-dependent, but ATF3-independent cell death
Parkinson's disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra (SN) and depletion of striatal dopamine (DA), leading to a range of motor symptoms, including resting tremor, rigidity, bradykinesia and postural abnormalities. The neurotoxin (MPTP...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652523/ https://ncbi.nlm.nih.gov/pubmed/23500530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2013.03.003 |
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