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The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-κB signaling, and inflammatory gene expression in human aortic valve cells

Bicuspid aortic valves calcify at a significantly higher rate than normal aortic valves, a process that involves increased inflammation. Because we have previously found that bicuspid aortic valve experience greater stretch, we investigated the potential connection between stretch and inflammation i...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:FASEB J
Κύριοι συγγραφείς: Patel, Vishal, Carrion, Katrina, Hollands, Andrew, Hinton, Andrew, Gallegos, Thomas, Dyo, Jeffrey, Sasik, Roman, Leire, Emma, Hardiman, Gary, Mohamed, Salah A., Nigam, Sanjay, King, Charles C., Nizet, Victor, Nigam, Vishal
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Federation of American Societies for Experimental Biology 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771066/
https://ncbi.nlm.nih.gov/pubmed/25630970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-257808
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