The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-κB signaling, and inflammatory gene expression in human aortic valve cells

Bicuspid aortic valves calcify at a significantly higher rate than normal aortic valves, a process that involves increased inflammation. Because we have previously found that bicuspid aortic valve experience greater stretch, we investigated the potential connection between stretch and inflammation i...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:FASEB J
المؤلفون الرئيسيون: Patel, Vishal, Carrion, Katrina, Hollands, Andrew, Hinton, Andrew, Gallegos, Thomas, Dyo, Jeffrey, Sasik, Roman, Leire, Emma, Hardiman, Gary, Mohamed, Salah A., Nigam, Sanjay, King, Charles C., Nizet, Victor, Nigam, Vishal
التنسيق: Artigo
اللغة:Inglês
منشور في: Federation of American Societies for Experimental Biology 2015
الموضوعات:
Research Communication
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771066/
https://ncbi.nlm.nih.gov/pubmed/25630970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-257808
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