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The Long Non-Coding HOTAIR Is Modulated by Cyclic Stretch and WNT/β-CATENIN in Human Aortic Valve Cells and Is a Novel Repressor of Calcification Genes

Aortic valve calcification is a significant and serious clinical problem for which there are no effective medical treatments. Individuals born with bicuspid aortic valves, 1–2% of the population, are at the highest risk of developing aortic valve calcification. Aortic valve calcification involves in...

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Detalhes bibliográficos
Main Authors: Carrion, Katrina, Dyo, Jeffrey, Patel, Vishal, Sasik, Roman, Mohamed, Salah A., Hardiman, Gary, Nigam, Vishal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006892/
https://ncbi.nlm.nih.gov/pubmed/24788418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096577
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