Cyclic stretch of Embryonic Cardiomyocytes Increases Proliferation, Growth, and Expression While Repressing Tgf-β Signaling

Perturbed biomechanical stimuli are thought to be critical for the pathogenesis of a number of congenital heart defects, including Hypoplastic Left Heart Syndrome (HLHS). While embryonic cardiomyocytes experience biomechanical stretch every heart beat, their molecular responses to biomechanical stim...

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Bibliografiske detaljer
Udgivet i:J Mol Cell Cardiol
Main Authors: Banerjee, Indroneal, Carrion, Katrina, Serrano, Ricardo, Dyo, Jeffrey, Sasik, Roman, Lund, Sean, Willems, Erik, Aceves, Seema, Meili, Rudolph, Mercola, Mark, Chen, Ju, Zambon, Alexander, Hardiman, Gary, Doherty, Taylor A, Lange, Stephan, del Álamo, Juan C., Nigam, Vishal
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302020/
https://ncbi.nlm.nih.gov/pubmed/25446186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.11.003
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