miR-486 is modulated by stretch and increases ventricular growth

Perturbations in biomechanical stimuli during cardiac development contribute to congenital cardiac defects such as hypoplastic left heart syndrome (HLHS). This study sought to identify stretch-responsive pathways involved in cardiac development. miRNA-Seq identified miR-486 as being increased in car...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Lange, Stephan, Banerjee, Indroneal, Carrion, Katrina, Serrano, Ricardo, Habich, Louisa, Kameny, Rebecca, Lengenfelder, Luisa, Dalton, Nancy, Meili, Rudolph, Börgeson, Emma, Peterson, Kirk, Ricci, Marco, Lincoln, Joy, Ghassemian, Majid, Fineman, Jeffery, del Álamo, Juan C., Nigam, Vishal
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795397/
https://ncbi.nlm.nih.gov/pubmed/31513548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125507
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