The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-κB signaling, and inflammatory gene expression in human aortic valve cells

Bicuspid aortic valves calcify at a significantly higher rate than normal aortic valves, a process that involves increased inflammation. Because we have previously found that bicuspid aortic valve experience greater stretch, we investigated the potential connection between stretch and inflammation i...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Patel, Vishal, Carrion, Katrina, Hollands, Andrew, Hinton, Andrew, Gallegos, Thomas, Dyo, Jeffrey, Sasik, Roman, Leire, Emma, Hardiman, Gary, Mohamed, Salah A., Nigam, Sanjay, King, Charles C., Nizet, Victor, Nigam, Vishal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2015
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771066/
https://ncbi.nlm.nih.gov/pubmed/25630970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-257808
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