Comparable Efficacy With Varying Dosages of Glucarpidase in Pediatric Oncology Patients

BACKGROUND: Glucarpidase rapidly reduces methotrexate plasma concentrations in patients experiencing methotrexate-induced renal dysfunction. Debate exists regarding the role of glucarpidase in therapy given its high cost. The use of reduced-dose glucarpidase has been reported, and may allow more ins...

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Bibliografische gegevens
Gepubliceerd in:Pediatr Blood Cancer
Hoofdauteurs: Scott, Jeffrey R., Zhou, Yinmei, Cheng, Cheng, Ward, Deborah A., Swanson, Hope D., Molinelli, Alejandro R., Stewart, Clinton F., Navid, Fariba, Jeha, Sima, Relling, Mary V., Crews, Kristine R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770903/
https://ncbi.nlm.nih.gov/pubmed/25631103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25395
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