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Gd(3+)-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic-2-Hydroxypropyl-β-Cyclodextrin/Pluronic Polyrotaxane as a Long Circulating High Relaxivity MRI Contrast Agent
A multivalent magnetic resonance imaging agent based on a 2-hydroxypropyl-β-cyclodextrin (HPCD):Pluronic F127 polyrotaxane carrier has been synthesized and its blood pool contrast properties characterized. This Gd(3+)-DO3A-HPCD/Pluronic polyrotaxane construct is shown to circulate for more than 30 m...
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| Publié dans: | ACS Appl Mater Interfaces |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4768309/ https://ncbi.nlm.nih.gov/pubmed/26417911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.5b05393 |
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