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Design, Synthesis, and Evaluation of 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid-Derived, Redox-Sensitive Contrast Agents for Magnetic Resonance Imaging

The design and synthesis of three 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid (DO3A) derivatives bearing linkers with terminal thiol groups and a preliminary evaluation of their potential for use in assembling redox-sensitive Magnetic Resonance Imaging (MRI) contrast agents are reported. The...

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Detalhes bibliográficos
Main Authors: Raghunand, Natarajan, Guntle, Gerald P., Gokhale, Vijay, Nichol, Gary S., Mash, Eugene A., Jagadish, Bhumasamudram
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941433/
https://ncbi.nlm.nih.gov/pubmed/20722424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100592u
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