IMPROVED SYNTHESIS OF 10-(2-ALKYLAMINO-2-OXOETHYL)-1,4,7,10-TETRAAZACYCLODODECANE-1,4,7-TRIACETIC ACID DERIVATIVES BEARING ACID-SENSITIVE LINKERS

Alkylation of the hydrobromide salts of 1,4,7-tris(methoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane and 1,4,7-tris(ethoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane with appropriate α-bromoacetamides, followed by hydrolysis, provides convenient access to 10-(2-alkylamino-2-oxoethyl)-1,4,7,10...

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Detalhes bibliográficos
Main Authors: Jagadish, Bhumasamudram, Ozumerzifon, Tarik J., Roberts, Sue A., Hall, Gabriel B., Mash, Eugene A., Raghunand, Natarajan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866964/
https://ncbi.nlm.nih.gov/pubmed/24363464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00397911.2013.813547
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