Synthesis of 2-Hydroxypropyl-β-cyclodextrin/Pluronic-Based Polyrotaxanes via Heterogeneous Reaction as Potential Niemann-Pick Type C Therapeutics

[Image: see text] Five polyrotaxanes were synthesized by threading 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) onto a variety of α,ω-ditriethylenediamino-N-carbamoyl-poly-(ethylene oxide)-block-poly(propylene oxide)-block-poly-(ethylene oxide) (Pluronic) triblock copolymers using a two-pot strategy und...

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Vydáno v:Biomacromolecules
Hlavní autoři: Mondjinou, Yawo A., McCauliff, Leslie A., Kulkarni, Aditya, Paul, Lake, Hyun, Seok-Hee, Zhang, Zhaorui, Wu, Zhen, Wirth, Mary, Storch, Judith, Thompson, David H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314287/
https://ncbi.nlm.nih.gov/pubmed/24180231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm400922a
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