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Pluronic based β-cyclodextrin polyrotaxanes for treatment of Niemann-Pick Type C disease
Niemann-Pick Type C disease (NPC) is a rare metabolic disorder characterized by disruption of normal cholesterol trafficking within the cells of the body. There are no FDA approved treatments available for NPC patients. Recently, the cycloheptaglucoside 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) has s...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5408228/ https://ncbi.nlm.nih.gov/pubmed/28452365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46737 |
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