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Hybrid Phase Ligation for Efficient Synthesis of Histone Proteins

We introduce a hybrid solid-solution phase ligation approach that combines the efficiency of solid phase ligation with solution phase ligation in the total synthesis of modified histone proteins. A two linker strategy allows analysis throughout work on the solid phase and maximizes yields through cl...

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Détails bibliographiques
Publié dans:Org Biomol Chem
Auteurs principaux: Yu, Ruixuan R., Mahto, Santosh K., Justus, Kurt, Alexander, Mallory M., Howard, Cecil J., Ottesen, Jennifer J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767651/
https://ncbi.nlm.nih.gov/pubmed/26821702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob02195b
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