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β-arrestin drives MAP kinase signaling from clathrin-coated structures after GPCR dissociation

β-arrestins critically regulate G protein-coupled receptor (GPCR) signaling, not only 'arresting' the G protein signal but also modulating endocytosis and initiating a discrete G protein-independent signal via MAP kinase(1–3). Despite enormous recent progress toward understanding biophysic...

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Bibliographic Details
Published in:Nat Cell Biol
Main Authors: Eichel, K., Jullié, D., von Zastrow, M.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767649/
https://ncbi.nlm.nih.gov/pubmed/26829388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3307
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