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Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification

Effective chemopreventive agents are needed against lung cancer, the leading cause of cancer death. Results from our previous work showed that dietary dihydromethysticin (DHM) effectively blocked initiation of lung tumorigenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mice, an...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Drug Metab Dispos
Päätekijät: Narayanapillai, Sreekanth C., von Weymarn, Linda B., Carmella, Steven G., Leitzman, Pablo, Paladino, Jordan, Upadhyaya, Pramod, Hecht, Stephen S., Murphy, Sharon E., Xing, Chengguo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767383/
https://ncbi.nlm.nih.gov/pubmed/26744252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.068387
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