Loading...

Pilot in vivo structure-activity relationship of dihydromethysticin in blocking 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced O(6)-methylguanine and lung tumor in A/J mice

(+)-Dihydromethysticin was recently identified as a promising lung cancer chemopreventive agent while (+)-dihydrokavain was completely ineffective. A pilot in vivo structure-activity relationship (SAR) was explored, evaluating the efficacy of its analogs in blocking 4-(methylnitrosamino)-1-(3-pyridy...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Med Chem
Main Authors: Puppala, Manohar, Narayanapillai, Sreekanth C., Leitzman, Pablo, Sun, Haifeng, Upadhyaya, Pramod, O’Sullivan, M. Gerard, Hecht, Stephen S., Xing, Chengguo
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729742/
https://ncbi.nlm.nih.gov/pubmed/28806079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b00921
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!