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Heterogeneity of leukemia-initiating capacity of chronic myelogenous leukemia stem cells
Chronic myelogenous leukemia (CML) results from transformation of a long-term hematopoietic stem cell (LTHSC) by expression of the BCR-ABL fusion gene. However, BCR-ABL–expressing LTHSCs are heterogeneous in their capacity as leukemic stem cells (LSCs). Although discrepancies in proliferative, self-...
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| Udgivet i: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4767357/ https://ncbi.nlm.nih.gov/pubmed/26878174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79196 |
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