Effective Targeting of Quiescent Chronic Myelogenous Leukemia Stem Cells by Histone Deacetylase Inhibitors in Combination with Imatinib Mesylate

Imatinib mesylate (IM) induces remission in chronic myelogenous leukemia (CML) patients but does not eliminate leukemia stem cells (LSC), which remain a potential source of relapse. Here we investigated the ability of HDAC inhibitors (HDACi) to target CML stem cells. Treatment with HDACi combined wi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Bin, Strauss, Adam C., Chu, Su, Li, Min, Ho, Yinwei, Shiang, Keh-Dong, Snyder, David S, Huettner, Claudia S., Shultz, Leonard, Holyoake, Tessa, Bhatia, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873971/
https://ncbi.nlm.nih.gov/pubmed/20478526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.03.011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados