Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment

Imatinib mesylate treatment markedly reduces the burden of leukemia cells in chronic myelogenous leukemia (CML) patients. However, patients remain at risk for relapse on discontinuing treatment. We have previously shown that residual BCR-ABL(+) progenitors can be detected in CML patients within the...

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Bibliographic Details
Main Authors: Chu, Su, McDonald, Tinisha, Lin, Allen, Chakraborty, Sujata, Huang, Qin, Snyder, David S., Bhatia, Ravi
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2011
Subjects:
Myeloid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217358/
https://ncbi.nlm.nih.gov/pubmed/21931114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-327437
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