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Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment

Imatinib mesylate treatment markedly reduces the burden of leukemia cells in chronic myelogenous leukemia (CML) patients. However, patients remain at risk for relapse on discontinuing treatment. We have previously shown that residual BCR-ABL(+) progenitors can be detected in CML patients within the...

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Detalhes bibliográficos
Main Authors: Chu, Su, McDonald, Tinisha, Lin, Allen, Chakraborty, Sujata, Huang, Qin, Snyder, David S., Bhatia, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217358/
https://ncbi.nlm.nih.gov/pubmed/21931114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-327437
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