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CRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataracts
Cataracts are the leading cause of vision loss in the world, although surgical treatment can restore vision in cataract patients. Until now, there have been no adequate animal models for in vivo studies of artificial lens safety and drug interactions. Genetic studies have demonstrated that GJA8 is i...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4766569/ https://ncbi.nlm.nih.gov/pubmed/26912477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22024 |
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