MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing

BACKGROUND: DNA methylation at a gene promoter region has the potential to regulate gene transcription. Patterns of methylation over multiple CpG sites in a region are often complex and cell type specific, with the region showing multiple allelic patterns in a sample. This complexity is commonly obs...

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Pubblicato in:BMC Bioinformatics
Autori principali: Wong, Nicholas C., Pope, Bernard J., Candiloro, Ida L., Korbie, Darren, Trau, Matt, Wong, Stephen Q., Mikeska, Thomas, Zhang, Xinmin, Pitman, Mark, Eggers, Stefanie, Doyle, Stephen R., Dobrovic, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Software
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765133/
https://ncbi.nlm.nih.gov/pubmed/26911705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0950-8
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