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Assessing combined methylation-sensitive high resolution melting and pyrosequencing for the analysis of heterogeneous DNA methylation

Heterogeneous DNA methylation leads to difficulties in accurate detection and quantification of methylation. Methylation-sensitive high resolution melting (MS-HRM) is unique among regularly used methods for DNA methylation analysis in that heterogeneous methylation can be readily identified, althoug...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Candiloro, Ida LM, Mikeska, Thomas, Dobrovic, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100767/
https://ncbi.nlm.nih.gov/pubmed/21364322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.4.14853
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