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Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes

Epigenetic silencing by promoter methylation of genes associated with cancer initiation and progression is a hallmark of tumour cells. As a consequence, testing for DNA methylation biomarkers in plasma or other body fluids shows great promise for detection of malignancies at early stages and/or for...

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Bibliografski detalji
Glavni autori: Kristensen, Lasse Sommer, Raynor, Michael, Candiloro, Ida, Dobrovic, Alexander
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380579/
https://ncbi.nlm.nih.gov/pubmed/22570110
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