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Genome-Wide Profiling of DNA Methylation Reveals a Class of Normally Methylated CpG Island Promoters

The role of CpG island methylation in normal development and cell differentiation is of keen interest, but remains poorly understood. We performed comprehensive DNA methylation profiling of promoter regions in normal peripheral blood by methylated CpG island amplification in combination with microar...

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Detalhes bibliográficos
Main Authors: Shen, Lanlan, Kondo, Yutaka, Guo, Yi, Zhang, Jiexin, Zhang, Li, Ahmed, Saira, Shu, Jingmin, Chen, Xinli, Waterland, Robert A, Issa, Jean-Pierre J
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041996/
https://ncbi.nlm.nih.gov/pubmed/17967063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030181
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