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Developmentally Programmed 3′ CpG Island Methylation Confers Tissue- and Cell-Type-Specific Transcriptional Activation

During development, a small but significant number of CpG islands (CGIs) become methylated. The timing of developmentally programmed CGI methylation and associated mechanisms of transcriptional regulation during cellular differentiation, however, remain poorly characterized. Here, we used genome-wid...

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Détails bibliographiques
Auteurs principaux: Yu, Da-Hai, Ware, Carol, Waterland, Robert A., Zhang, Jiexin, Chen, Miao-Hsueh, Gadkari, Manasi, Kunde-Ramamoorthy, Govindarajan, Nosavanh, Lagina M., Shen, Lanlan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624169/
https://ncbi.nlm.nih.gov/pubmed/23459939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01124-12
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