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Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation

In this article, we show that high resolution melting analysis (HRM) is a sensitive and specific method for the detection of methylation. Methylated DNA and unmethylated DNA acquire different sequences after bisulphite treatment resulting in PCR products with markedly different melting profiles. We...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wojdacz, Tomasz K., Dobrovic, Alexander
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874596/
https://ncbi.nlm.nih.gov/pubmed/17289753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm013
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