Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility

Approximately 25–30% of colorectal cancer (CRC) cases are expected to result from a genetic predisposition, but in only 5–10% of these cases highly penetrant germline mutations are found. The remaining CRC heritability is still unexplained, and may be caused by a hitherto-undefined set of rare varia...

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Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: de Voer, Richarda M., Hahn, Marc-Manuel, Weren, Robbert D. A., Mensenkamp, Arjen R., Gilissen, Christian, van Zelst-Stams, Wendy A., Spruijt, Liesbeth, Kets, C. Marleen, Zhang, Junxiao, Venselaar, Hanka, Vreede, Lilian, Schubert, Nil, Tychon, Marloes, Derks, Ronny, Schackert, Hans K., Geurts van Kessel, Ad, Hoogerbrugge, Nicoline, Ligtenberg, Marjolijn J. L., Kuiper, Roland P.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764646/
https://ncbi.nlm.nih.gov/pubmed/26901136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005880
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