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Candidate Gene Discovery in Hereditary Colorectal Cancer and Polyposis Syndromes–Considerations for Future Studies

To discover novel high-penetrant risk loci for hereditary colorectal cancer (hCRC) and polyposis syndromes many whole-exome and whole-genome sequencing (WES/WGS) studies have been performed. Remarkably, these studies resulted in only a few novel high-penetrant risk genes. Given this observation, the...

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Publicat a:Int J Mol Sci
Autors principals: te Paske, Iris B. A. W., Ligtenberg, Marjolijn J. L., Hoogerbrugge, Nicoline, de Voer, Richarda M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699508/
https://ncbi.nlm.nih.gov/pubmed/33228212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228757
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