Germline deletions in the tumour suppressor gene FOCAD are associated with polyposis and colorectal cancer development

Heritable genetic variants can significantly affect the lifetime risk of developing cancer, including polyposis and colorectal cancer (CRC). Variants in genes currently known to be associated with a high risk for polyposis or CRC, however, explain only a limited number of hereditary cases. The ident...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Pathol
Главные авторы: Weren, Robbert DA, Venkatachalam, Ramprasath, Cazier, Jean‐Baptiste, Farin, Henner F, Kets, C Marleen, de Voer, Richarda M, Vreede, Lilian, Verwiel, Eugène TP, van Asseldonk, Monique, Kamping, Eveline J, Kiemeney, Lambertus A, Neveling, Kornelia, Aben, Katja KH, Carvajal‐Carmona, Luis, Nagtegaal, Iris D, Schackert, Hans K, Clevers, Hans, van de Wetering, Marc, Tomlinson, Ian P, Ligtenberg, Marjolijn JL, Hoogerbrugge, Nicoline, Geurts van Kessel, Ad, Kuiper, Roland P
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Ltd 2015
Предметы:
Original Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681464/
https://ncbi.nlm.nih.gov/pubmed/25712196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4520
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы