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Molecular mechanisms of cardiomyopathy phenotypes associated with myosin light chain mutations

We discuss here the potential mechanisms of action associated with hypertrophic (HCM) or dilated (DCM) cardiomyopathy causing mutations in the myosin regulatory (RLC) and essential (ELC) light chains. Specifically, we focus on four HCM mutations: RLC-A13T, RLC-K104E, ELC-A57G and ELC-M173V, and one...

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Detalhes bibliográficos
Publicado no:J Muscle Res Cell Motil
Main Authors: Huang, Wenrui, Szczesna-Cordary, Danuta
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764388/
https://ncbi.nlm.nih.gov/pubmed/26385864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-015-9423-3
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