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Molecular mechanisms of cardiomyopathy phenotypes associated with myosin light chain mutations

We discuss here the potential mechanisms of action associated with hypertrophic (HCM) or dilated (DCM) cardiomyopathy causing mutations in the myosin regulatory (RLC) and essential (ELC) light chains. Specifically, we focus on four HCM mutations: RLC-A13T, RLC-K104E, ELC-A57G and ELC-M173V, and one...

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Publicado en:J Muscle Res Cell Motil
Autores principales: Huang, Wenrui, Szczesna-Cordary, Danuta
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764388/
https://ncbi.nlm.nih.gov/pubmed/26385864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-015-9423-3
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