Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension

Idiopathic pulmonary fibrosis (IPF) is a lethal, fibroproliferative disease. Pulmonary hypertension (PH) can develop secondary to IPF and increase mortality. Alternatively, activated macrophages (AAMs) contribute to the pathogenesis of both IPF and PH. Here we hypothesized that adenosine signaling t...

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Udgivet i:FASEB J
Main Authors: Karmouty-Quintana, Harry, Philip, Kemly, Acero, Luis F., Chen, Ning-Yuan, Weng, Tingting, Molina, Jose G., Luo, Fayong, Davies, Jonathan, Le, Ngoc-Bao, Bunge, Isabelle, Volcik, Kelly A., Le, Thanh-Thuy T., Johnston, Richard A., Xia, Yang, Eltzschig, Holger K., Blackburn, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2015
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763976/
https://ncbi.nlm.nih.gov/pubmed/25318478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-260182
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