Coordination of ENT2-dependent adenosine transport and signaling dampens mucosal inflammation

Intestinal epithelial barrier repair is vital for remission in inflammatory bowel disease (IBD). Extracellular adenosine signaling has been implicated in promoting restoration of epithelial barrier function. Currently, no clinically approved agents target this pathway. Adenosine signaling is termina...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Aherne, Carol M., Collins, Colm B., Rapp, Caroline R., Olli, Kristine E., Perrenoud, Loni, Jedlicka, Paul, Bowser, Jessica L., Mills, Tingting W., Karmouty-Quintana, Harry, Blackburn, Michael R., Eltzschig, Holger K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237472/
https://ncbi.nlm.nih.gov/pubmed/30333323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121521
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