Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury

The signaling molecule adenosine has been implicated in attenuating acute lung injury (ALI). Adenosine signaling is terminated by its uptake through equilibrative nucleoside transporters (ENTs). We hypothesized that ENT-dependent adenosine uptake could be targeted to enhance adenosine-mediated lung...

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Bibliografiske detaljer
Main Authors: Eckle, Tobias, Hughes, Kelly, Ehrentraut, Heidi, Brodsky, Kelley S., Rosenberger, Peter, Choi, Doo-Sup, Ravid, Katya, Weng, Tingting, Xia, Yang, Blackburn, Michael R., Eltzschig, Holger K.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2013
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714574/
https://ncbi.nlm.nih.gov/pubmed/23603835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-228551
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