Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury

The signaling molecule adenosine has been implicated in attenuating acute lung injury (ALI). Adenosine signaling is terminated by its uptake through equilibrative nucleoside transporters (ENTs). We hypothesized that ENT-dependent adenosine uptake could be targeted to enhance adenosine-mediated lung...

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Autori principali: Eckle, Tobias, Hughes, Kelly, Ehrentraut, Heidi, Brodsky, Kelley S., Rosenberger, Peter, Choi, Doo-Sup, Ravid, Katya, Weng, Tingting, Xia, Yang, Blackburn, Michael R., Eltzschig, Holger K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2013
Soggetti:
Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714574/
https://ncbi.nlm.nih.gov/pubmed/23603835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-228551
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