Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension

Idiopathic pulmonary fibrosis (IPF) is a lethal, fibroproliferative disease. Pulmonary hypertension (PH) can develop secondary to IPF and increase mortality. Alternatively, activated macrophages (AAMs) contribute to the pathogenesis of both IPF and PH. Here we hypothesized that adenosine signaling t...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Karmouty-Quintana, Harry, Philip, Kemly, Acero, Luis F., Chen, Ning-Yuan, Weng, Tingting, Molina, Jose G., Luo, Fayong, Davies, Jonathan, Le, Ngoc-Bao, Bunge, Isabelle, Volcik, Kelly A., Le, Thanh-Thuy T., Johnston, Richard A., Xia, Yang, Eltzschig, Holger K., Blackburn, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763976/
https://ncbi.nlm.nih.gov/pubmed/25318478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-260182
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