Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD

Intratumoral heterogeneity is an inherent feature of most human cancers and has profound implications for cancer therapy. As a result, there is an emergent need to explore previously unmapped mechanisms regulating distinct subpopulations of tumor cells and to understand their contribution to tumor p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cortez, Eliane, Gladh, Hanna, Braun, Sebastian, Bocci, Matteo, Cordero, Eugenia, Björkström, Niklas K., Miyazaki, Hideki, Michael, Iacovos P., Eriksson, Ulf, Folestad, Erika, Pietras, Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763770/
https://ncbi.nlm.nih.gov/pubmed/26831065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509384113
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