Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting

BACKGROUND: Important support functions, including promotion of tumor growth, angiogenesis, and invasion, have been attributed to the different cell types populating the tumor stroma, i.e., endothelial cells, cancer-associated fibroblasts, pericytes, and infiltrating inflammatory cells. Fibroblasts...

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Bibliographische Detailangaben
Hauptverfasser: Pietras, Kristian, Pahler, Jessica, Bergers, Gabriele, Hanahan, Douglas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214790/
https://ncbi.nlm.nih.gov/pubmed/18232728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050019
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