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Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting
BACKGROUND: Important support functions, including promotion of tumor growth, angiogenesis, and invasion, have been attributed to the different cell types populating the tumor stroma, i.e., endothelial cells, cancer-associated fibroblasts, pericytes, and infiltrating inflammatory cells. Fibroblasts...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2008
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2214790/ https://ncbi.nlm.nih.gov/pubmed/18232728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050019 |
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