Specific targeting of PDGFRβ in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression

PDGF-BB/PDGFRβ signaling plays an important role during vascularization by mediating pericyte recruitment to the vasculature, promoting the integrity and function of vessels. Until now it has not been possible to assess the specific role of PDGFRβ signaling in tumor progression and angiogenesis due...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Theranostics
Main Authors: Tsioumpekou, Maria, Cunha, Sara I., Ma, Haisha, Åhgren, Aive, Cedervall, Jessica, Olsson, Anna-Karin, Heldin, Carl-Henrik, Lennartsson, Johan
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2020
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956815/
https://ncbi.nlm.nih.gov/pubmed/31938055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37851
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki