Specific targeting of PDGFRβ in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression

PDGF-BB/PDGFRβ signaling plays an important role during vascularization by mediating pericyte recruitment to the vasculature, promoting the integrity and function of vessels. Until now it has not been possible to assess the specific role of PDGFRβ signaling in tumor progression and angiogenesis due...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Theranostics
Egile Nagusiak: Tsioumpekou, Maria, Cunha, Sara I., Ma, Haisha, Åhgren, Aive, Cedervall, Jessica, Olsson, Anna-Karin, Heldin, Carl-Henrik, Lennartsson, Johan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ivyspring International Publisher 2020
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956815/
https://ncbi.nlm.nih.gov/pubmed/31938055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37851
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