Specific targeting of PDGFRβ in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression

PDGF-BB/PDGFRβ signaling plays an important role during vascularization by mediating pericyte recruitment to the vasculature, promoting the integrity and function of vessels. Until now it has not been possible to assess the specific role of PDGFRβ signaling in tumor progression and angiogenesis due...

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Enregistré dans:
Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Tsioumpekou, Maria, Cunha, Sara I., Ma, Haisha, Åhgren, Aive, Cedervall, Jessica, Olsson, Anna-Karin, Heldin, Carl-Henrik, Lennartsson, Johan
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956815/
https://ncbi.nlm.nih.gov/pubmed/31938055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37851
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