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In-cell thermodynamics and a new role for protein surfaces

There is abundant, physiologically relevant knowledge about protein cores; they are hydrophobic, exquisitely well packed, and nearly all hydrogen bonds are satisfied. An equivalent understanding of protein surfaces has remained elusive because proteins are almost exclusively studied in vitro in simp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Smith, Austin E., Zhou, Larry Z., Gorensek, Annelise H., Senske, Michael, Pielak, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763743/
https://ncbi.nlm.nih.gov/pubmed/26755596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518620113
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