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Osmotic Shock Induced Protein Destabilization in Living Cells and Its Reversal by Glycine Betaine

Many organisms can adapt to changes in the solute content of their surroundings (i.e., the osmolarity). Hyperosmotic shock causes water efflux and a concomitant reduction in cell volume, which is countered by the accumulation of osmolytes. This volume reduction increases the crowded nature of the cy...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Stadmiller, Samantha S., Gorensek-Benitez, Annelise H., Guseman, Alex J., Pielak, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985519/
https://ncbi.nlm.nih.gov/pubmed/28263768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.03.001
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