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Quantifying the Temperature Dependence of Glycine Betaine RNA Duplex Destabilization
Glycine betaine stabilizes folded protein structure due to its unfavorable thermodynamic interactions with amide oxygen and aliphatic carbon surface area exposed during protein unfolding. However, glycine betaine can attenuate nucleic acid secondary structure stability, although its mechanism of des...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3886373/ https://ncbi.nlm.nih.gov/pubmed/24219229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400765d |
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