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Quantifying the Temperature Dependence of Glycine Betaine RNA Duplex Destabilization

Glycine betaine stabilizes folded protein structure due to its unfavorable thermodynamic interactions with amide oxygen and aliphatic carbon surface area exposed during protein unfolding. However, glycine betaine can attenuate nucleic acid secondary structure stability, although its mechanism of des...

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書目詳細資料
Main Authors: Schwinefus, Jeffrey J., Menssen, Ryan J., Kohler, James M., Schmidt, Elliot C., Thomas, Alexandra L.
格式: Artigo
語言:Inglês
出版: 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886373/
https://ncbi.nlm.nih.gov/pubmed/24219229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400765d
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