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Roles of mutation and recombination in the evolution of protein thermodynamics
We present a comprehensive study of the evolutionary origin of the thermodynamic behavior of proteins. With the use of a simplified model, we exhaustively enumerate the space of all sequences and the space of all structures, simulate the evolutionary relationship between sequences and structures, an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124923/ https://ncbi.nlm.nih.gov/pubmed/12149452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162097799 |
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