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Potential role of phenotypic mutations in the evolution of protein expression and stability

Phenotypic mutations (errors occurring during protein synthesis) are orders of magnitude more frequent than genetic mutations. Consequently, the sequences of individual protein molecules transcribed and translated from the same gene can differ. To test the effects of such mutations, we established a...

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Bibliografiske detaljer
Main Authors: Goldsmith, Moshe, Tawfik, Dan S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669386/
https://ncbi.nlm.nih.gov/pubmed/19339491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809506106
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