Thermodynamic System Drift in Protein Evolution

Proteins from thermophiles are generally more thermostable than their mesophilic homologs, but little is known about the evolutionary process driving these differences. Here we attempt to understand how the diverse thermostabilities of bacterial ribonuclease H1 (RNH) proteins evolved. RNH proteins f...

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Bibliografske podrobnosti
izdano v:PLoS Biol
Main Authors: Hart, Kathryn M., Harms, Michael J., Schmidt, Bryan H., Elya, Carolyn, Thornton, Joseph W., Marqusee, Susan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227636/
https://ncbi.nlm.nih.gov/pubmed/25386647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001994
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