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Thermodynamic System Drift in Protein Evolution
Proteins from thermophiles are generally more thermostable than their mesophilic homologs, but little is known about the evolutionary process driving these differences. Here we attempt to understand how the diverse thermostabilities of bacterial ribonuclease H1 (RNH) proteins evolved. RNH proteins f...
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Publicado no: | PLoS Biol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4227636/ https://ncbi.nlm.nih.gov/pubmed/25386647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001994 |
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